Histopathological study of non healing ulcers of skin in patients attending tertiary care hospital

Brij Mohan Kumar Singh, Arijit Bishnu, Barnini Banerjee

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Clinico-pathological correlation of non-healing ulcer provides an utmost important clue in the spectrum of this debilitating condition. Little information is available in the outcome of the ulcers when they underwent surgical biopsy for determination in the causation of these conditions. Therefore, the relative incidence and etiology of non-healing ulcer was assessed retrospectively after retrieving the cases of non-healing ulcer from the department of Pathology, Kasturba Medical College, Manipal. A total of 75 cases were studied in this regard and were compared with their Clinical presentation which were retrieved from their case files. As compared to the west, were venous and diabetic ulcer predominate, in the developing nations the most frequent cause of a non-healing ulcer are malignancy (n=25) followed by chronic diseases like tuberculosis (n=20). In this study, various risk factors involved in the causation of non-healing ulcer were also compared and was found to be having a greater impact and should not be kept aside. Thus beside a good and accurate clinical diagnosis, early biopsy to rule out malignancy and identify the etiology is mandatory for a better clinico-pathological.

Original languageEnglish
Pages (from-to)434-443
Number of pages10
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Issue number3
Publication statusPublished - 2016

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


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