TY - JOUR
T1 - Impact of nutrient-gene-interaction on periodontal diseasesan over view
AU - Haidrus, Razia
AU - Nayak, Sangeeta U.
AU - Kamath, Deepa G.
N1 - Publisher Copyright:
© 2020, Institute of Medico-Legal Publications. All rights reserved.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2020/10/1
Y1 - 2020/10/1
N2 - The key role to maintain equilibrium between microbial challenge and host response is played by nutrition, which is also important in various chronic diseases like cardiovascular disease, type 2 diabetes & rheumatoid arthritis. An individual’s baseline inflammatory position is influenced by macronutrients & micronutrients which modulate pro inflammatory and anti-inflammatory cascades. The aim of this review is to give an insight on mechanism of action of various macronutrients, micronutrients and some of the trace elements with their positive effects in resolution of various chronic diseases such as diabetes, cardiovascular, cancer and periodontal diseases. Thus dietary changes can be associated with genetic composition, this in turn may be due to changes in individual response. This highlights the significance of unravelling the role of nutrient gene interaction in progression of chronic diseases. Periodontitis is linked to a number of chronic systemic diseases which emphasize the significance of effective periodontal disease management for tooth retention as well as for overall health.
AB - The key role to maintain equilibrium between microbial challenge and host response is played by nutrition, which is also important in various chronic diseases like cardiovascular disease, type 2 diabetes & rheumatoid arthritis. An individual’s baseline inflammatory position is influenced by macronutrients & micronutrients which modulate pro inflammatory and anti-inflammatory cascades. The aim of this review is to give an insight on mechanism of action of various macronutrients, micronutrients and some of the trace elements with their positive effects in resolution of various chronic diseases such as diabetes, cardiovascular, cancer and periodontal diseases. Thus dietary changes can be associated with genetic composition, this in turn may be due to changes in individual response. This highlights the significance of unravelling the role of nutrient gene interaction in progression of chronic diseases. Periodontitis is linked to a number of chronic systemic diseases which emphasize the significance of effective periodontal disease management for tooth retention as well as for overall health.
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U2 - 10.37506/ijfmt.v14i4.11520
DO - 10.37506/ijfmt.v14i4.11520
M3 - Article
AN - SCOPUS:85100014692
SN - 0973-9122
VL - 14
SP - 457
EP - 463
JO - Journal of Forensic Medicine and Toxicology
JF - Journal of Forensic Medicine and Toxicology
IS - 4
ER -