TY - JOUR
T1 - Impact of wastewater from different sources on the prevalence of antimicrobial-resistant Escherichia coli in sewage treatment plants in South India
AU - Akiba, Masato
AU - Senba, Hironobu
AU - Otagiri, Haruna
AU - Prabhasankar, Valipparambil P.
AU - Taniyasu, Sachi
AU - Yamashita, Nobuyoshi
AU - Lee, Ken ichi
AU - Yamamoto, Takehisa
AU - Tsutsui, Toshiyuki
AU - Ian Joshua, Derrick
AU - Balakrishna, Keshava
AU - Bairy, Indira
AU - Iwata, Taketoshi
AU - Kusumoto, Masahiro
AU - Kannan, Kurunthachalam
AU - Guruge, Keerthi S.
PY - 2015/5/1
Y1 - 2015/5/1
N2 - The sewage treatment plant (STP) is one of the most important interfaces between the human population and the aquatic environment, leading to contamination of the latter by antimicrobial-resistant bacteria. To identify factors affecting the prevalence of antimicrobial-resistant bacteria, water samples were collected from three different STPs in South India. STP1 exclusively treats sewage generated by a domestic population. STP2 predominantly treats sewage generated by a domestic population with a mix of hospital effluent. STP3 treats effluents generated exclusively by a hospital. The water samples were collected between three intermediate treatment steps including equalization, aeration, and clarification, in addition to the outlet to assess the removal rates of bacteria as the effluent passed through the treatment plant. The samples were collected in three different seasons to study the effect of seasonal variation. Escherichia coli isolated from the water samples were tested for susceptibility to 12 antimicrobials. The results of logistic regression analysis suggest that the hospital wastewater inflow significantly increased the prevalence of antimicrobial-resistant E. coli, whereas the treatment processes and sampling seasons did not affect the prevalence of these isolates. A bias in the genotype distribution of E. coli was observed among the isolates obtained from STP3. In conclusion, hospital wastewaters should be carefully treated to prevent the contamination of Indian environment with antimicrobial-resistant bacteria.
AB - The sewage treatment plant (STP) is one of the most important interfaces between the human population and the aquatic environment, leading to contamination of the latter by antimicrobial-resistant bacteria. To identify factors affecting the prevalence of antimicrobial-resistant bacteria, water samples were collected from three different STPs in South India. STP1 exclusively treats sewage generated by a domestic population. STP2 predominantly treats sewage generated by a domestic population with a mix of hospital effluent. STP3 treats effluents generated exclusively by a hospital. The water samples were collected between three intermediate treatment steps including equalization, aeration, and clarification, in addition to the outlet to assess the removal rates of bacteria as the effluent passed through the treatment plant. The samples were collected in three different seasons to study the effect of seasonal variation. Escherichia coli isolated from the water samples were tested for susceptibility to 12 antimicrobials. The results of logistic regression analysis suggest that the hospital wastewater inflow significantly increased the prevalence of antimicrobial-resistant E. coli, whereas the treatment processes and sampling seasons did not affect the prevalence of these isolates. A bias in the genotype distribution of E. coli was observed among the isolates obtained from STP3. In conclusion, hospital wastewaters should be carefully treated to prevent the contamination of Indian environment with antimicrobial-resistant bacteria.
UR - http://www.scopus.com/inward/record.url?scp=84923061635&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84923061635&partnerID=8YFLogxK
U2 - 10.1016/j.ecoenv.2015.02.018
DO - 10.1016/j.ecoenv.2015.02.018
M3 - Article
C2 - 25704279
AN - SCOPUS:84923061635
SN - 0147-6513
VL - 115
SP - 203
EP - 208
JO - Ecotoxicology and Environmental Safety
JF - Ecotoxicology and Environmental Safety
ER -
