In vitro antioxidant studies of Annona squamosa Linn. Leaves

A. Shirwaikar, K. Rajendran, C.D. Kumar

Research output: Contribution to journalArticlepeer-review

105 Citations (SciVal)


The free radical scavenging potential of the leaves of A. squamosa was studied by using different antioxidant models of screening. The ethanolic extract at 1000 μg/ ml showed maximum scavenging of the radical cation, 2,2- azinobis- (3-ethylbenzothiazoline- 6- sulphonate) (ABTS) observed upto 99.07% followed by the scavenging of the stable radical 1,1-diphenyl, 2- picryl hydrazyl (DPPH) (89.77%) and nitric oxide radical (73.64%) at the same concentration. However, the extract showed only moderate scavenging activity of superoxide radicals and antilipid peroxidation potential, which was performed using rat- brain homogenate. The findings justify the therapeutic applications of the plant in the indigenous system of medicine, augmenting its therapeutic value.
Original languageEnglish
Pages (from-to)803-807
Number of pages5
JournalIndian Journal of Experimental Biology
Issue number8
Publication statusPublished - 2004


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