TY - JOUR
T1 - In vitro antioxidant studies of Annona squamosa Linn. Leaves
AU - Shirwaikar, A.
AU - Rajendran, K.
AU - Kumar, C.D.
N1 - Cited By :90
Export Date: 10 November 2017
CODEN: IJEBA
Correspondence Address: Shirwaikar, A.; Department of Pharmacognosy, College of Pharmaceutical Sciences, Manipal 576 104, India; email: [email protected]
Chemicals/CAS: Antioxidants; Free Radical Scavengers; Plant Extracts
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PY - 2004
Y1 - 2004
N2 - The free radical scavenging potential of the leaves of A. squamosa was studied by using different antioxidant models of screening. The ethanolic extract at 1000 μg/ ml showed maximum scavenging of the radical cation, 2,2- azinobis- (3-ethylbenzothiazoline- 6- sulphonate) (ABTS) observed upto 99.07% followed by the scavenging of the stable radical 1,1-diphenyl, 2- picryl hydrazyl (DPPH) (89.77%) and nitric oxide radical (73.64%) at the same concentration. However, the extract showed only moderate scavenging activity of superoxide radicals and antilipid peroxidation potential, which was performed using rat- brain homogenate. The findings justify the therapeutic applications of the plant in the indigenous system of medicine, augmenting its therapeutic value.
AB - The free radical scavenging potential of the leaves of A. squamosa was studied by using different antioxidant models of screening. The ethanolic extract at 1000 μg/ ml showed maximum scavenging of the radical cation, 2,2- azinobis- (3-ethylbenzothiazoline- 6- sulphonate) (ABTS) observed upto 99.07% followed by the scavenging of the stable radical 1,1-diphenyl, 2- picryl hydrazyl (DPPH) (89.77%) and nitric oxide radical (73.64%) at the same concentration. However, the extract showed only moderate scavenging activity of superoxide radicals and antilipid peroxidation potential, which was performed using rat- brain homogenate. The findings justify the therapeutic applications of the plant in the indigenous system of medicine, augmenting its therapeutic value.
M3 - Article
SN - 0019-5189
VL - 42
SP - 803
EP - 807
JO - Indian Journal of Experimental Biology
JF - Indian Journal of Experimental Biology
IS - 8
ER -