TY - JOUR
T1 - Inflammatory Myofibroblastic Tumor
T2 - A Rapidly Growing Soft Tissue Mass in the Posterior Mandible
AU - Sah, Parul
AU - Byatnal, Aditi Amit
AU - Rao, Lakshmi
AU - Narayanaswamy, Venkadasalapathy
AU - Radhakrishnan, Raghu
PY - 2013/12
Y1 - 2013/12
N2 - The term inflammatory myofibroblastic tumor (IMT) encompasses a diverse group of spindle cell entities that traverses a clinical and histologic spectrum, extending from reactive to benign neoplastic to highly aggressive with malignant inclinations. Head and neck IMTs are rarely seen and comprise less than 5 % of tumors. Here we report a case of a 30 year old male who presented with a rapidly enlarging and extremely painful growth in the right posterior mandible, post extraction. Histopathological examination revealed a highly cellular connective tissue stroma comprised of spindle shaped cells arranged in fascicles, admixed with inflammatory cells, predominantly plasma cells. Apart from routine hematological investigations, serum protein electrophoresis was also performed. The final diagnosis was confirmed by a panel of immunomarkers consisting of MPO, CD34, CD20, CD3, CD23, CD138, SMA and ALK. To the best of our knowledge, this is the third case of oral IMT arising from an extraction socket.
AB - The term inflammatory myofibroblastic tumor (IMT) encompasses a diverse group of spindle cell entities that traverses a clinical and histologic spectrum, extending from reactive to benign neoplastic to highly aggressive with malignant inclinations. Head and neck IMTs are rarely seen and comprise less than 5 % of tumors. Here we report a case of a 30 year old male who presented with a rapidly enlarging and extremely painful growth in the right posterior mandible, post extraction. Histopathological examination revealed a highly cellular connective tissue stroma comprised of spindle shaped cells arranged in fascicles, admixed with inflammatory cells, predominantly plasma cells. Apart from routine hematological investigations, serum protein electrophoresis was also performed. The final diagnosis was confirmed by a panel of immunomarkers consisting of MPO, CD34, CD20, CD3, CD23, CD138, SMA and ALK. To the best of our knowledge, this is the third case of oral IMT arising from an extraction socket.
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U2 - 10.1007/s12105-013-0474-8
DO - 10.1007/s12105-013-0474-8
M3 - Article
C2 - 23843049
AN - SCOPUS:84886748435
SN - 1936-055X
VL - 7
SP - 393
EP - 397
JO - Head and Neck Pathology
JF - Head and Neck Pathology
IS - 4
ER -