Influence of blood pressure and rheology on oscillatory shear index and wall shear stress in the carotid artery

Nitesh Kumar, R. Pai, S. M. Abdul Khader, S. H. Khan, P. A. Kyriacou

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Atherosclerosis is a localized complication dependent on both the rheology and the arterial response to blood pressure. Fluid–structure interaction (FSI) study can be effectively used to understand the local haemodynamics and study the development and progression of atherosclerosis. Although numerical investigations of atherosclerosis are well documented, research on the influence of blood pressure as a result of the response to physio–social factors like anxiety, mental stress, and exercise is scarce. In this work, a three-dimensional (3D) Fluid–Structure Interaction (FSI) study was carried out for normal and stenosed patient-specific carotid artery models. Haemodynamic parameters such as Wall Shear Stress (WSS) and Oscillatory Shear Index (OSI) are evaluated for normal and hypertension conditions. The Carreau–Yasuda blood viscosity model was used in the FSI simulations, and the results are compared with the Newtonian model. The results reveal that high blood pressure increases the peripheral resistance, thereby reducing the WSS. Higher OSI occurs in the region with high flow recirculation. Variation of WSS due to changes in blood pressure and blood viscosity is important in understanding the haemodynamics of carotid arteries. This study demonstrates the potential of FSI to understand the causes of atherosclerosis due to altered blood pressures.

Original languageEnglish
Article number510
JournalJournal of the Brazilian Society of Mechanical Sciences and Engineering
Issue number11
Publication statusPublished - 11-2022

All Science Journal Classification (ASJC) codes

  • Automotive Engineering
  • Aerospace Engineering
  • General Engineering
  • Mechanical Engineering
  • Industrial and Manufacturing Engineering
  • Applied Mathematics


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