Inhibition of radiation-induced lipid peroxidation by curcumin

N. Sreejayan; M.N.A. Rao; K.I. Priyadarsini; T.P.A. Devasagayam

doi:10.1016/S0378-5173(97)04900-4

Inhibition of radiation-induced lipid peroxidation by curcumin

N. Sreejayan, M.N.A. Rao, K.I. Priyadarsini, T.P.A. Devasagayam

Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

84 Citations (Scopus)

Abstract

The ability of curcumin, a natural antioxidant from turmeric, to inhibit radiation-induced lipid peroxidation in rat liver microsomes was examined. Curcumin was incorporated into microsomes during ultracentrifugation. The antioxidant has significant time- and concentration-dependent inhibitory effect on lipid peroxidation induced by τ-radiation. Inhibition of lipid peroxidation was also observed in microsomes samples previously saturated with N2O.

Original language	Undefined/Unknown
Pages (from-to)	127-130
Number of pages	4
Journal	International Journal of Pharmaceutics
Volume	151
Issue number	1
DOIs	https://doi.org/10.1016/S0378-5173(97)04900-4
Publication status	Published - 1997

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10.1016/S0378-5173(97)04900-4

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Cite this

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title = "Inhibition of radiation-induced lipid peroxidation by curcumin",

abstract = "The ability of curcumin, a natural antioxidant from turmeric, to inhibit radiation-induced lipid peroxidation in rat liver microsomes was examined. Curcumin was incorporated into microsomes during ultracentrifugation. The antioxidant has significant time- and concentration-dependent inhibitory effect on lipid peroxidation induced by τ-radiation. Inhibition of lipid peroxidation was also observed in microsomes samples previously saturated with N2O.",

author = "N. Sreejayan and M.N.A. Rao and K.I. Priyadarsini and T.P.A. Devasagayam",

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AU - Rao, M.N.A.

AU - Priyadarsini, K.I.

AU - Devasagayam, T.P.A.

N1 - cited By 63

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AB - The ability of curcumin, a natural antioxidant from turmeric, to inhibit radiation-induced lipid peroxidation in rat liver microsomes was examined. Curcumin was incorporated into microsomes during ultracentrifugation. The antioxidant has significant time- and concentration-dependent inhibitory effect on lipid peroxidation induced by τ-radiation. Inhibition of lipid peroxidation was also observed in microsomes samples previously saturated with N2O.

U2 - 10.1016/S0378-5173(97)04900-4

DO - 10.1016/S0378-5173(97)04900-4

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EP - 130

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