Intradural Hemangioendothelioma of Lumbar Spine: Dilemmas and Differentials in Diagnosis

Anusha S. Bhatt, Vikram Muthusubramanian, Asokan Kondappan, Anita Mahadevan

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1 Citation (Scopus)


Background: Vascular tumors of the spine range from benign hemangiomas to malignant angiosarcomas. Hemangioendotheliomas of spine are tumors of intermediate-grade malignancy with rare occurrence in the intradural location. The imaging and histopathologic features may mimic other common lesions occurring at this location. Case Description: A 70-year-old woman presented with lower limb weakness and sensory impairment along the L5–S1 dermatome. A radiologic diagnosis of neurofibroma at the intradural location of the L4–L5 level was made, and total excision of the space-occupying lesion was done. Histopathologic examination, however, revealed a vascular tumor consistent with hemangioendothelioma, which was confirmed by immunohistochemical analysis. We present this case discussing the dilemmas and difficulties in arriving at the diagnosis, highlighting the role of immunohistochemical aid. Conclusion: Histomorphology, aided by ancillar tests like immunohistochemistry, remains the criterion for the definitive diagnosis of such rare lesions, and pathologists need to be aware of these lesions occurring in uncommon locations.

Original languageEnglish
Pages (from-to)479-483
Number of pages5
JournalWorld Neurosurgery
Publication statusPublished - 10-2019

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology


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