TY - JOUR
T1 - Isolation and characterization of phytoconstituents from stem of elytranthe parasitica(L.) danser
AU - Kumar, N.
AU - Lobo, R.
AU - Mathew, J. E.
N1 - Funding Information:
We are grateful to DST-SERB (Department of Science and Technology, Science and Engineering Research Board) [File no: SB/YS/LS-10/2013], Government of India for providing financial support. Our sincere thanks to Manipal College of Pharmaceutical Sciences and Manipal Academy of Higher Education for providing the infrastructural facility and resources to carry out the research work.
Publisher Copyright:
© RASĀYAN. All rights reserved.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Mistletoes have earned a strong profile in treating cancer. Elytranthe parasitica (L.) Danser (EP), a hemi-parasitic plant belonging to Mistletoe family or Loranthaceae is known for its potent anti-cancer properties. Exploring the phytochemistry by isolating and characterizing phytoconstituents from unidentified mistletoes such as Elytranthe parasitica (L.) Danser would prove useful for cancer therapy. Stem parts of Elytranthe parasitica were extracted with methanol and sequentially fractionated with solvents in the increasing order of polarity. The diethyl ether fraction was selected for bioactivity guided fractionation. Fractionation was performed via gel filtration chromatography and analytical TLC to isolate the phytochemical(s). Activity guided fractionation led to the isolation of two phenolic compounds and two phytosterols: a phenolic acid (gallic acid), a flavanone (pinostrobin), a triterpenoid (lupeol) and a phytosterol (ß-sitosterol).
AB - Mistletoes have earned a strong profile in treating cancer. Elytranthe parasitica (L.) Danser (EP), a hemi-parasitic plant belonging to Mistletoe family or Loranthaceae is known for its potent anti-cancer properties. Exploring the phytochemistry by isolating and characterizing phytoconstituents from unidentified mistletoes such as Elytranthe parasitica (L.) Danser would prove useful for cancer therapy. Stem parts of Elytranthe parasitica were extracted with methanol and sequentially fractionated with solvents in the increasing order of polarity. The diethyl ether fraction was selected for bioactivity guided fractionation. Fractionation was performed via gel filtration chromatography and analytical TLC to isolate the phytochemical(s). Activity guided fractionation led to the isolation of two phenolic compounds and two phytosterols: a phenolic acid (gallic acid), a flavanone (pinostrobin), a triterpenoid (lupeol) and a phytosterol (ß-sitosterol).
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U2 - 10.31788/RJC.2020.1346062
DO - 10.31788/RJC.2020.1346062
M3 - Article
AN - SCOPUS:85095574382
SN - 0974-1496
VL - 13
SP - 2281
EP - 2289
JO - Rasayan Journal of Chemistry
JF - Rasayan Journal of Chemistry
IS - 4
ER -
