Isoniazid-induced pure red cell aplasia

Subraya Krishna Holla; Basavaprabhu Achappa; Pavan Manibettu Raguram; Sitamahalakshminagasai Yerramsetti

doi:10.1136/bcr-2018-226134

Isoniazid-induced pure red cell aplasia

Subraya Krishna Holla
, Basavaprabhu Achappa^*
, Pavan Manibettu Raguram
, Sitamahalakshminagasai Yerramsetti

^*Corresponding author for this work

Department of General Medicine, Kasturba Medical College, Mangalore

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The pure red cell aplasia (PRCA) is an uncommon side effect of isoniazid. We describe a 28-year-old man who developed a severe anaemia caused by PRCA. The patient received antituberculous therapy including isoniazid for his pulmonary tuberculosis. On discontinuation of isoniazid, the anaemia recovered promptly. PRCA should be considered in case of unexplained anaemia during isoniazid treatment.

Original language	English
Article number	bcr-2018-226134
Journal	BMJ Case Reports
Volume	2018
DOIs	https://doi.org/10.1136/bcr-2018-226134
Publication status	Published - 01-01-2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

General Medicine

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10.1136/bcr-2018-226134

Cite this

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abstract = "The pure red cell aplasia (PRCA) is an uncommon side effect of isoniazid. We describe a 28-year-old man who developed a severe anaemia caused by PRCA. The patient received antituberculous therapy including isoniazid for his pulmonary tuberculosis. On discontinuation of isoniazid, the anaemia recovered promptly. PRCA should be considered in case of unexplained anaemia during isoniazid treatment.",

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N2 - The pure red cell aplasia (PRCA) is an uncommon side effect of isoniazid. We describe a 28-year-old man who developed a severe anaemia caused by PRCA. The patient received antituberculous therapy including isoniazid for his pulmonary tuberculosis. On discontinuation of isoniazid, the anaemia recovered promptly. PRCA should be considered in case of unexplained anaemia during isoniazid treatment.

AB - The pure red cell aplasia (PRCA) is an uncommon side effect of isoniazid. We describe a 28-year-old man who developed a severe anaemia caused by PRCA. The patient received antituberculous therapy including isoniazid for his pulmonary tuberculosis. On discontinuation of isoniazid, the anaemia recovered promptly. PRCA should be considered in case of unexplained anaemia during isoniazid treatment.

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ER -

Isoniazid-induced pure red cell aplasia

Abstract

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