L-asparaginase-induced hypofibrinogenemia: A case report

O. Balaji; D. Amita; P. Navin

doi:10.22159/ajpcr.2017.v10i5.17320

L-asparaginase-induced hypofibrinogenemia: A case report

O. Balaji, D. Amita, P. Navin^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Anticancer therapy is always known to cause various side effects. L-asparaginase used in the treatment of adult T-cell lymphoblastic leukemia is a novel class of drug, an enzyme produced from plants as well as microorganisms except human. It is known to cause various adverse reactions including life-threatening neurological complications and thrombotic disorders. Hence, we report a case of hypofibrinogenemia associated with L-asparaginase in a patient treated for T-cell adult lymphoblastic leukemia.

Original language	English
Pages (from-to)	11-12
Number of pages	2
Journal	Asian Journal of Pharmaceutical and Clinical Research
Volume	10
Issue number	5
DOIs	https://doi.org/10.22159/ajpcr.2017.v10i5.17320
Publication status	Published - 01-01-2017
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmaceutical Science
Pharmacology (medical)

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10.22159/ajpcr.2017.v10i5.17320

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title = "L-asparaginase-induced hypofibrinogenemia: A case report",

abstract = "Anticancer therapy is always known to cause various side effects. L-asparaginase used in the treatment of adult T-cell lymphoblastic leukemia is a novel class of drug, an enzyme produced from plants as well as microorganisms except human. It is known to cause various adverse reactions including life-threatening neurological complications and thrombotic disorders. Hence, we report a case of hypofibrinogenemia associated with L-asparaginase in a patient treated for T-cell adult lymphoblastic leukemia.",

author = "O. Balaji and D. Amita and P. Navin",

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AU - Navin, P.

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AB - Anticancer therapy is always known to cause various side effects. L-asparaginase used in the treatment of adult T-cell lymphoblastic leukemia is a novel class of drug, an enzyme produced from plants as well as microorganisms except human. It is known to cause various adverse reactions including life-threatening neurological complications and thrombotic disorders. Hence, we report a case of hypofibrinogenemia associated with L-asparaginase in a patient treated for T-cell adult lymphoblastic leukemia.

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JF - Asian Journal of Pharmaceutical and Clinical Research

IS - 5

ER -

L-asparaginase-induced hypofibrinogenemia: A case report

Abstract

All Science Journal Classification (ASJC) codes

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