TY - JOUR
T1 - Label-Free Biomolecule Detection with InP/AlGaAs Charge Plasma Dielectric-Modulated Vertical TFET Using TaN as Metal Gate
AU - Elshafie, Hashim
AU - Alqahtani, Abdulrahman Saad
AU - Mubarakali, Azath
AU - Adarsh Rag, S.
AU - Venkatesh, M.
AU - Parthasarathy, P.
N1 - Publisher Copyright:
© 2013 IEEE.
PY - 2025
Y1 - 2025
N2 - This study introduces a label-free biosensing method for biomolecule detection utilizing an InP/AlGaAs charge plasma dielectric-modulated vertical tunnel field-effect transistor (InP/AlGaAs VTFET) featuring TaN as the metal gate. The device comprises a nanocavity beneath the gate metal adjacent to the tunnelling junction, where biomolecules engage with the dielectric material, resulting in fluctuations in the drain current. A twin metal gate architecture with laterally split dielectrics is employed to eliminate short-channel effects. The biosensor has exceptional sensitivity, attaining a peak drain current sensitivity of 2.5 × 10 cm2 for biomolecules such as albumin (k = 7). The gadget proficiently identifies biomolecules with varying dielectric constants and charge distributions, enabling adaptable label-free detection of diverse targets. The study examines the influence of dielectric constant on critical metrics such as Energy Band Diagrams, Drain Current, Drain Sensitivity, and subthreshold swing (SS). The overlap between the source and pocket regions, along with the introduction of an auxiliary gate, optimizes the electrical characteristics. Simulation results show that the proposed InP/AlGaAs VTFET achieves a maximum sensitivity of 3.5 × 103, outperforming configurations without overlap (2 × 103), highlights the potential of proposed InP/AlGaAs VTFET for scalable, high-sensitivity, label-free biomolecule detection.
AB - This study introduces a label-free biosensing method for biomolecule detection utilizing an InP/AlGaAs charge plasma dielectric-modulated vertical tunnel field-effect transistor (InP/AlGaAs VTFET) featuring TaN as the metal gate. The device comprises a nanocavity beneath the gate metal adjacent to the tunnelling junction, where biomolecules engage with the dielectric material, resulting in fluctuations in the drain current. A twin metal gate architecture with laterally split dielectrics is employed to eliminate short-channel effects. The biosensor has exceptional sensitivity, attaining a peak drain current sensitivity of 2.5 × 10 cm2 for biomolecules such as albumin (k = 7). The gadget proficiently identifies biomolecules with varying dielectric constants and charge distributions, enabling adaptable label-free detection of diverse targets. The study examines the influence of dielectric constant on critical metrics such as Energy Band Diagrams, Drain Current, Drain Sensitivity, and subthreshold swing (SS). The overlap between the source and pocket regions, along with the introduction of an auxiliary gate, optimizes the electrical characteristics. Simulation results show that the proposed InP/AlGaAs VTFET achieves a maximum sensitivity of 3.5 × 103, outperforming configurations without overlap (2 × 103), highlights the potential of proposed InP/AlGaAs VTFET for scalable, high-sensitivity, label-free biomolecule detection.
UR - https://www.scopus.com/pages/publications/105006513941
UR - https://www.scopus.com/pages/publications/105006513941#tab=citedBy
U2 - 10.1109/ACCESS.2025.3570233
DO - 10.1109/ACCESS.2025.3570233
M3 - Article
AN - SCOPUS:105006513941
SN - 2169-3536
VL - 13
SP - 89667
EP - 89684
JO - IEEE Access
JF - IEEE Access
ER -