TY - JOUR
T1 - Langerhans cell histiocytosis of mediastinal node
AU - Khadilkar, Urmila N.
AU - Rao, A. T.K.
AU - Sahoo, Kausalya Kumari
AU - Pai, Mukta R.
PY - 2008/3/1
Y1 - 2008/3/1
N2 - The predominant clinical and radiological features of Langerhans Cell Histiocytosis (LCH) in children are due to osseous involvement. Extra-osseous disease is far less common, occurring in association with bone disease or in isolation. In the present study, LCH was presumptively diagnosed on Ultrasound guided Fine needle aspiration cytology (FNAC) of the mediastinal lymph node in a 18 month-old child. The diagnosis was confirmed by histological examination of the biopsy material. S-100 protein localization in the LCH cells is often positive on immunohistochemistry.
AB - The predominant clinical and radiological features of Langerhans Cell Histiocytosis (LCH) in children are due to osseous involvement. Extra-osseous disease is far less common, occurring in association with bone disease or in isolation. In the present study, LCH was presumptively diagnosed on Ultrasound guided Fine needle aspiration cytology (FNAC) of the mediastinal lymph node in a 18 month-old child. The diagnosis was confirmed by histological examination of the biopsy material. S-100 protein localization in the LCH cells is often positive on immunohistochemistry.
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U2 - 10.1007/s12098-008-0064-z
DO - 10.1007/s12098-008-0064-z
M3 - Article
C2 - 18376103
AN - SCOPUS:44049094308
SN - 0972-9607
VL - 75
SP - 294
EP - 296
JO - Indian Journal of Practical Pediatrics
JF - Indian Journal of Practical Pediatrics
IS - 3
ER -