Langerhans cell histiocytosis of mediastinal node

Urmila N. Khadilkar, A. T.K. Rao, Kausalya Kumari Sahoo, Mukta R. Pai

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


The predominant clinical and radiological features of Langerhans Cell Histiocytosis (LCH) in children are due to osseous involvement. Extra-osseous disease is far less common, occurring in association with bone disease or in isolation. In the present study, LCH was presumptively diagnosed on Ultrasound guided Fine needle aspiration cytology (FNAC) of the mediastinal lymph node in a 18 month-old child. The diagnosis was confirmed by histological examination of the biopsy material. S-100 protein localization in the LCH cells is often positive on immunohistochemistry.

Original languageEnglish
Pages (from-to)294-296
Number of pages3
JournalIndian Journal of Pediatrics
Issue number3
Publication statusPublished - 01-03-2008

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health


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