Langerhans cell histiocytosis presenting as hypothyroid goitre: A unique presentation

Krishna Chaitanya Marupudi, Suman S. Karanth, Joseph Thomas

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Langerhans cell histiocytosis (LCH) is a disease involving the antigen presenting cells, which can range from a single system involvement with an indolent course to a multisystem disease with increased morbidity. We present a rare case of LCH presenting as hypothyroid goitre that was successfully treated as per the LCH III trial protocol with a combination of vinblastine and oral prednisolone. We highlight the need for awareness of this rare presentation of LCH as a painless goitre which is often misdiagnosed as poorly differentiated thyroid carcinoma or overlooked as a benign disease.

Original languageEnglish
Article number206760
JournalBMJ Case Reports
Publication statusPublished - 02-12-2014

All Science Journal Classification (ASJC) codes

  • General Medicine


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