Lhermitte′s sign: The current status

Supreet Khare, Deeksha Seth

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Lhermitte′s sign was described by Marie and Chatelin and named after Jean Lhermitte. This sign is mostly described as an electric shock like condition by some patients of multiple sclerosis. This sensation occurs when the neck is moved in a wrong way or rather flexed. It can also travel down to the spine, arms, and legs, and sometimes the trunk. Demyelination and hyperexcitability are the main pathophysiological reasons depicted for the Lhermitte′s sign. Other causes for Lhermitte′s sign include transverse myelitis, behηet′s disease, trauma, etc. This article reviews the Lhermitte′s sign, its history, and its etiopathophysiology. Very few studies are available on Lermitte′s sign and more research need to be done on the same to ensure its sensitivity and specificity.

Original languageEnglish
Pages (from-to)154-156
Number of pages3
JournalAnnals of Indian Academy of Neurology
Issue number2
Publication statusPublished - 01-01-2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Clinical Neurology


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