Background: Low Level Laser Therapy (LLLT) is an emerging treatment modality for management of neuropathic pain. It works by triggering biochemical changes with in cells. Objective: This systematic review focused on finding evidence on the effectiveness of LLLT on treatment of painful diabetic neuropathy. Methods: We conducted a systematic review (PubMed, Web of Science, CINAHL and Cochrane) to find the evidence on effectiveness of LLLT on treatment of painful diabetic neuropathy. Randomized and non-randomized studies were included in the review. Results: A total of 627 studies were screened. After the exclusion criteria (duplicate, animal studies, LLLT for treating other neuralgias) 6 studies were included in the study. The outcome measure that were considered were the difference in pain score and nerve conduction velocity test and quality of life questionnaire. Conclusion: The evidence obtained shows LLLT has a positive effect in controlling diabetic neuropathic pain.

Original languageEnglish
Pages (from-to)2667-2670
Number of pages4
JournalDiabetes and Metabolic Syndrome: Clinical Research and Reviews
Issue number4
Publication statusPublished - 01-07-2019

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism


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