LSPR-Based Sensing of Insulin Using Gold Nanostars

N. D. Prajna, C. Santhosh, Devasia Tom, K. Sinha Rajeev*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The noble metal nanoparticles like gold and silver because of their distinct size and shape-dependent optical properties have been used widely in the field of biosensing. Insulin is an important peptide hormone that regulates blood glucose levels in the body. In this work, surfactant-free gold nanostars were synthesized by a one-pot seedless method and were used for sensing Insulin. A parabolic trend in the LSPR peak positions of nanostars was observed with increasing Insulin concentration. A sensitivity of 288nm/nM and a detection limit of 8.6 pM was achieved at lower insulin concentrations.

Original languageEnglish
Title of host publicationAIP Conference Proceedings
EditorsH. Shankar, P. Thangaraj, K. Mohana Sundaram
PublisherAmerican Institute of Physics Inc.
Edition1
ISBN (Electronic)9780735447653
DOIs
Publication statusPublished - 15-12-2023
Event3rd International Conference on Advances in Physical Sciences and Materials: ICAPSM 2022 - Hybrid, Coimbatore, India
Duration: 18-08-202219-08-2022

Publication series

NameAIP Conference Proceedings
Number1
Volume2901
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference3rd International Conference on Advances in Physical Sciences and Materials: ICAPSM 2022
Country/TerritoryIndia
CityHybrid, Coimbatore
Period18-08-2219-08-22

All Science Journal Classification (ASJC) codes

  • General Physics and Astronomy

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