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Machine learning-enhanced two-photon microscopy for the detection of esophageal cancer progression through collagen analysis

  • Kausalya Neelavara Makkithaya
  • , Ming Che Chan
  • , Wei Shiuan Tseng
  • , Nirmal Mazumder
  • , Guan Yu Zhuo*
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We demonstrate a novel approach combining two-photon microscopy with machine learning algorithms to analyze collagen organization in esophageal tissues, enabling differentiation between squamous cell carcinoma and high-grade dysplasia through quantitative extracellular matrix assessment.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2025
PublisherOptical Society of America
ISBN (Electronic)9781557528001
DOIs
Publication statusPublished - 2025
Event2025 European Conference on Biomedical Optics, ECBO 2025 - Munich, Germany
Duration: 22-06-202526-06-2025

Publication series

NameEuropean Conference on Biomedical Optics, ECBO 2025

Conference

Conference2025 European Conference on Biomedical Optics, ECBO 2025
Country/TerritoryGermany
CityMunich
Period22-06-2526-06-25

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Biomaterials
  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

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