TY - JOUR
T1 - Medicinal plants used in the treatment of human immunodeficiency virus
AU - Salehi, Bahare
AU - Anil Kumar, Nanjangud V.
AU - Şener, Bilge
AU - Sharifi-Rad, Mehdi
AU - Kılıç, Mehtap
AU - Mahady, Gail B.
AU - Vlaisavljevic, Sanja
AU - Iriti, Marcello
AU - Kobarfard, Farzad
AU - Setzer, William N.
AU - Ayatollahi, Seyed Abdulmajid
AU - Ata, Athar
AU - Sharifi-Rad, Javad
PY - 2018/5/14
Y1 - 2018/5/14
N2 - Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.
AB - Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.
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U2 - 10.3390/ijms19051459
DO - 10.3390/ijms19051459
M3 - Review article
AN - SCOPUS:85047056765
SN - 1661-6596
VL - 19
JO - International Journal of Molecular Sciences
JF - International Journal of Molecular Sciences
IS - 5
M1 - 1459
ER -
