Micronuclei-induction and its correlation to cell survival in HeLa cells treated with different doses of adriamycin

Ganesh Chandra Jagetia; Vijayashree Nayak

doi:10.1016/S0304-3835(96)04470-9

Micronuclei-induction and its correlation to cell survival in HeLa cells treated with different doses of adriamycin

Ganesh Chandra Jagetia^*
, Vijayashree Nayak

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The treatment of HeLa cells with different concentrations of adriamycin (0, 5, 10, 25, 50 and 100 μg/ml) resulted in a significant and dose-dependent decline in the cell survival. Conversely, the frequency of micronuclei increased in a concentration-dependent manner. The micronuclei-induction and cell survival were found to be inversely related.

Original language	English
Pages (from-to)	123-128
Number of pages	6
Journal	Cancer Letters
Volume	110
Issue number	1-2
DOIs	https://doi.org/10.1016/S0304-3835(96)04470-9
Publication status	Published - 20-12-1996
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Cancer Research
Molecular Biology
Oncology

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10.1016/S0304-3835(96)04470-9

Cite this

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title = "Micronuclei-induction and its correlation to cell survival in HeLa cells treated with different doses of adriamycin",

abstract = "The treatment of HeLa cells with different concentrations of adriamycin (0, 5, 10, 25, 50 and 100 μg/ml) resulted in a significant and dose-dependent decline in the cell survival. Conversely, the frequency of micronuclei increased in a concentration-dependent manner. The micronuclei-induction and cell survival were found to be inversely related.",

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AB - The treatment of HeLa cells with different concentrations of adriamycin (0, 5, 10, 25, 50 and 100 μg/ml) resulted in a significant and dose-dependent decline in the cell survival. Conversely, the frequency of micronuclei increased in a concentration-dependent manner. The micronuclei-induction and cell survival were found to be inversely related.

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U2 - 10.1016/S0304-3835(96)04470-9

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JO - Cancer Letters

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ER -

Micronuclei-induction and its correlation to cell survival in HeLa cells treated with different doses of adriamycin

Abstract

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All Science Journal Classification (ASJC) codes

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