TY - JOUR
T1 - Molybdenum-based hetero-nanocomposites for cancer therapy, diagnosis and biosensing application
T2 - Current advancement and future breakthroughs
AU - Dhas, Namdev
AU - Kudarha, Ritu
AU - Garkal, Atul
AU - Ghate, Vivek
AU - Sharma, Shilpa
AU - Panzade, Prabhakar
AU - Khot, Shubham
AU - Chaudhari, Pinal
AU - Singh, Ashutosh
AU - Paryani, Mitali
AU - Lewis, Shaila
AU - Garg, Neha
AU - Singh, Narinder
AU - Bangar, Priyanka
AU - Mehta, Tejal
N1 - Funding Information:
Authors would like to thank Council of Scientific and Industrial Research (CSIR) -India, Department of Science and Technology ( DST)-INSPIRE-India and Nirma University-India for providing financial assistances in the form of CSIR-SRF and Nirma University fellowship-JRF respectively to Namdev Dhas (09/1048(007)/2018-EMR-I), and Ritu Kudarha (No. DST/INSPIRE Fellowship/2015/IF150242) Atul Garkal (NU/Ph.D./IP/GAD /19-20/1496)), respectively.
Publisher Copyright:
© 2020 Elsevier B.V.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2021/2/10
Y1 - 2021/2/10
N2 - In recent years, there have been significant advancements in the nanotechnology for cancer therapy. Even though molybdenum disulphide (MoS2)-based nanocomposites demonstrated extensive applications in biosensing, bioimaging, phototherapy, the review article focusing on MoS2 nanocomposite platform has not been accounted for yet. The review summarizes recent strategies on design and fabrication of MoS2-based nanocomposites and their modulated properties in cancer treatment. The review also discussed several therapeutic strategies (photothermal, photodynamic, immunotherapy, gene therapy and chemotherapy) and their combinations for efficient cancer therapy along with certain case studies. The review also inculcates various diagnostic techniques viz. magnetic resonance imaging, computed tomography, photoacoustic imaging and fluorescence imaging for diagnosis of cancer.
AB - In recent years, there have been significant advancements in the nanotechnology for cancer therapy. Even though molybdenum disulphide (MoS2)-based nanocomposites demonstrated extensive applications in biosensing, bioimaging, phototherapy, the review article focusing on MoS2 nanocomposite platform has not been accounted for yet. The review summarizes recent strategies on design and fabrication of MoS2-based nanocomposites and their modulated properties in cancer treatment. The review also discussed several therapeutic strategies (photothermal, photodynamic, immunotherapy, gene therapy and chemotherapy) and their combinations for efficient cancer therapy along with certain case studies. The review also inculcates various diagnostic techniques viz. magnetic resonance imaging, computed tomography, photoacoustic imaging and fluorescence imaging for diagnosis of cancer.
UR - http://www.scopus.com/inward/record.url?scp=85098091403&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85098091403&partnerID=8YFLogxK
U2 - 10.1016/j.jconrel.2020.12.015
DO - 10.1016/j.jconrel.2020.12.015
M3 - Review article
AN - SCOPUS:85098091403
SN - 0168-3659
VL - 330
SP - 257
EP - 283
JO - Journal of Controlled Release
JF - Journal of Controlled Release
ER -
