TY - JOUR
T1 - Mucinous Tubular and Spindle Cell Carcinoma
T2 - A Review of Histopathology and Clinical and Prognostic Implications
AU - Nathany, Shrinidhi
AU - Monappa, Vidya
N1 - Publisher Copyright:
© 2020 College of American Pathologists. All rights reserved.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Mucinous tubular and spindle cell carcinomas are rare kidney tumors with generally indolent behavior. As the name suggests, classic histomorphology reveals bland spindle cells, tubules, and mucinous stroma. Uncommon histologic features include mucin-poor stroma, high nuclear grade, cellular pleomorphism, and presence of necrosis. Rare cases can show aggressive growth and distant metastasis. Mucinous tubular and spindle cell carcinoma has characteristic chromosomal abnormalities and the molecular signature remains the same, irrespective of the varied histomorphology.
AB - Mucinous tubular and spindle cell carcinomas are rare kidney tumors with generally indolent behavior. As the name suggests, classic histomorphology reveals bland spindle cells, tubules, and mucinous stroma. Uncommon histologic features include mucin-poor stroma, high nuclear grade, cellular pleomorphism, and presence of necrosis. Rare cases can show aggressive growth and distant metastasis. Mucinous tubular and spindle cell carcinoma has characteristic chromosomal abnormalities and the molecular signature remains the same, irrespective of the varied histomorphology.
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U2 - 10.5858/arpa.2017-0506-RS
DO - 10.5858/arpa.2017-0506-RS
M3 - Article
C2 - 30865490
AN - SCOPUS:85077274854
SN - 0003-9985
VL - 144
SP - 115
EP - 118
JO - Archives of pathology & laboratory medicine
JF - Archives of pathology & laboratory medicine
IS - 1
ER -