Multifunctional liposome-quantum dot hybrid nanocarriers for drug targeting to brain tumors

Brain-related drug delivery systems have always been a challenge for researchers as they require drugs to be delivered across the BBB. The combination of liposomes with semiconductor quantum dots, known as a liposomal QD hybrid system (L-QD), has good potential to achieve both required functions, i.e., imaging and therapeutic. Most of the targeting and biocompatible capacity of QDs is greatly modified by encapsulation with liposomes. It integrates the photochemical property of QD with the physiochemical and the pharmacodynamic properties of liposomes. Moreover, utilization of this particular hybrid gives options for doctors to check the efficacy and progress of treatment continuously until the end of therapy. QDs remain one of the pivotal nanotechnologies to be integrated in biological settings. Its encapsulation within liposomes can avoid chemical functionalization, which may lead to improved stability in plasma, improvement in biocompatibility, and better control of the pharmacological fate.