Nanoparticulate disinfection in endodontics

Research output: Contribution to journalReview articlepeer-review


Endodontic biofilms and the complexity of root canal systems are considered as major causes of primary and secondary root canal infection. Unfortunately, these biofilms contain bacteria which are well within dentinal tubules and are inaccessible to the conventional instrumentation, irrigants, intracanal medicaments, and sealers. Nanoparticles (NPs) are microscopic particles with one or more dimensions in the range of 1-100 nm. It has been observed that the size of nanoparticulates used in disinfection of the root canal, plays an important role in their antibacterial activity by overcoming microbial challenges, mechanical integrity of diseased dentin matrix, and tissue regeneration. This purpose of this review article is to provide the application of various nanoparticles in the control of biofilm formation with the root canal system.

Original languageEnglish
Pages (from-to)161-171
Number of pages11
JournalInternational Journal of Clinical Dentistry
Issue number3
Publication statusPublished - 01-01-2018

All Science Journal Classification (ASJC) codes

  • Dentistry(all)


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