Neonatal thyrotoxicosis with maternal hypothyroidism

Shruthi Ravindra; Sahana Shetty

doi:10.1136/bcr-2021-247865

Neonatal thyrotoxicosis with maternal hypothyroidism

Shruthi Ravindra
, Sahana Shetty^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Neonatal Graves' is uncommon, but a potentially fatal condition caused by transplacental transfer of thyroid stimulating immunoglobulin (TSI). It is seen in 1%-5% of infants born to a mother with Graves' disease. Here, we report a unique case of transient neonatal thyrotoxicosis with positive TSI in a premature neonate born to the mother with primary hypothyroidism. A short course of antithyroid drug treatment leads to significant clinical and biochemical improvement followed by complete recovery.

Original language	English
Article number	e247865
Journal	BMJ Case Reports
Volume	15
Issue number	3
DOIs	https://doi.org/10.1136/bcr-2021-247865
Publication status	Published - 09-03-2022

All Science Journal Classification (ASJC) codes

General Medicine

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10.1136/bcr-2021-247865

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title = "Neonatal thyrotoxicosis with maternal hypothyroidism",

abstract = "Neonatal Graves' is uncommon, but a potentially fatal condition caused by transplacental transfer of thyroid stimulating immunoglobulin (TSI). It is seen in 1\%-5\% of infants born to a mother with Graves' disease. Here, we report a unique case of transient neonatal thyrotoxicosis with positive TSI in a premature neonate born to the mother with primary hypothyroidism. A short course of antithyroid drug treatment leads to significant clinical and biochemical improvement followed by complete recovery.",

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AB - Neonatal Graves' is uncommon, but a potentially fatal condition caused by transplacental transfer of thyroid stimulating immunoglobulin (TSI). It is seen in 1%-5% of infants born to a mother with Graves' disease. Here, we report a unique case of transient neonatal thyrotoxicosis with positive TSI in a premature neonate born to the mother with primary hypothyroidism. A short course of antithyroid drug treatment leads to significant clinical and biochemical improvement followed by complete recovery.

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Neonatal thyrotoxicosis with maternal hypothyroidism

Abstract

All Science Journal Classification (ASJC) codes

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