Nephrotic syndrome in a child infected with Toxocara canis

A. K. Shetty, D. H. Aviles

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Toxocara canis is a common worldwide dog ascarid, and is acquired by ingestion of the parasitic eggs, which are shed in the feces of infected dogs. The clinical presentation, visceral larva migrans, is usually a disease of children, typically characterized by fever, hepatomegaly, pulmonary manifestations, leukocytosis, peristent eosinophilia, and hypergammaglobulinemia. The clinical course is usually benign and self-limited . Renal involvement with T canis infection is very unusual. This case report describes nephrotic syndrome (NS) in a 7-year-old boy coincident with a Toxocara canis infection. This rare association was confirmed by elevated Toxocara-specific IgM titers. Treatment with corticosteroids resulted in remission of his renal symptoms as well as abatement of T canis infection. The relationship between T canis infection and glomerular disease is still unclear. NS may represent another manifestation of T canis infection.

Original languageEnglish
JournalJournal of Investigative Medicine
Issue number2
Publication statusPublished - 01-01-1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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