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Neuromorphic computing for modeling neurological and psychiatric disorders: implications for drug development

  • Amisha S. Raikar
  • , J. Andrew*
  • , Pranjali Prabhu Dessai
  • , Sweta M. Prabhu
  • , Shounak Jathar
  • , Aishwarya Prabhu
  • , Mayuri B. Naik
  • , Gokuldas Vedant S. Raikar
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The emergence of neuromorphic computing, inspired by the structure and function of the human brain, presents a transformative framework for modelling neurological disorders in drug development. This article investigates the implications of applying neuromorphic computing to simulate and comprehend complex neural systems affected by conditions like Alzheimer’s, Parkinson’s, and epilepsy, drawing from extensive literature. It explores the intersection of neuromorphic computing with neurology and pharmaceutical development, emphasizing the significance of understanding neural processes and integrating deep learning techniques. Technical considerations, such as integrating neural circuits into CMOS technology and employing memristive devices for synaptic emulation, are discussed. The review evaluates how neuromorphic computing optimizes drug discovery and improves clinical trials by precisely simulating biological systems. It also examines the role of neuromorphic models in comprehending and simulating neurological disorders, facilitating targeted treatment development. Recent progress in neuromorphic drug discovery is highlighted, indicating the potential for transformative therapeutic interventions. As technology advances, the synergy between neuromorphic computing and neuroscience holds promise for revolutionizing the study of the human brain’s complexities and addressing neurological challenges.

Original languageEnglish
Article number318
JournalArtificial Intelligence Review
Volume57
Issue number12
DOIs
Publication statusPublished - 12-2024

All Science Journal Classification (ASJC) codes

  • Language and Linguistics
  • Linguistics and Language
  • Artificial Intelligence

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