New benzoxazoles as potential antitumor agents

S.G. Kini; G. Saraswat; A.M. Gandhi

New benzoxazoles as potential antitumor agents

S.G. Kini
, G. Saraswat
, A.M. Gandhi

Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

2-Aryl benzoxazols were synthesized by refluxing o-aminophenol with substituted benzoic acids in the presence of polyphosphoric acid. The screening for antitumour activity was done as per the National Cancer Institute Drug Screening Strategy 1985. Three compounds were found to be significantly cytotoxic as compared to Cisplatin against the EAC induced mice.

Original language	English
Pages (from-to)	99-100
Number of pages	2
Journal	Indian Journal of Heterocyclic Chemistry
Volume	15
Issue number	1
Publication status	Published - 2005

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SDG 3 Good Health and Well-being

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title = "New benzoxazoles as potential antitumor agents",

abstract = "2-Aryl benzoxazols were synthesized by refluxing o-aminophenol with substituted benzoic acids in the presence of polyphosphoric acid. The screening for antitumour activity was done as per the National Cancer Institute Drug Screening Strategy 1985. Three compounds were found to be significantly cytotoxic as compared to Cisplatin against the EAC induced mice.",

author = "S.G. Kini and G. Saraswat and A.M. Gandhi",

note = "Cited By :2 Export Date: 10 November 2017 Correspondence Address: Kini, S.G.; Department of Chemistry, Manipal College of Pharmaceutical Sciences, Manipal-576 104, India References: (2000) Chem. Abstr., pp. 265194s; Hill, R.P., Kallman, R.F., (1987) Experimental Cancer Therapy, p. 114; Meyer, B.H., Ferrigni, N.R., McLaughlin, J.L., (1982) Planta Med., 45, p. 31; Ghosh, M.N., (1984) Fundamentals of Experimental Pharmacology, p. 53. , Scientific Book Agency",

year = "2005",

language = "English",

volume = "15",

pages = "99--100",

journal = "Indian Journal of Heterocyclic Chemistry",

issn = "0971-1627",

publisher = "Connect Journals",

number = "1",

}

TY - JOUR

T1 - New benzoxazoles as potential antitumor agents

AU - Kini, S.G.

AU - Saraswat, G.

AU - Gandhi, A.M.

N1 - Cited By :2 Export Date: 10 November 2017 Correspondence Address: Kini, S.G.; Department of Chemistry, Manipal College of Pharmaceutical Sciences, Manipal-576 104, India References: (2000) Chem. Abstr., pp. 265194s; Hill, R.P., Kallman, R.F., (1987) Experimental Cancer Therapy, p. 114; Meyer, B.H., Ferrigni, N.R., McLaughlin, J.L., (1982) Planta Med., 45, p. 31; Ghosh, M.N., (1984) Fundamentals of Experimental Pharmacology, p. 53. , Scientific Book Agency

PY - 2005

Y1 - 2005

N2 - 2-Aryl benzoxazols were synthesized by refluxing o-aminophenol with substituted benzoic acids in the presence of polyphosphoric acid. The screening for antitumour activity was done as per the National Cancer Institute Drug Screening Strategy 1985. Three compounds were found to be significantly cytotoxic as compared to Cisplatin against the EAC induced mice.

AB - 2-Aryl benzoxazols were synthesized by refluxing o-aminophenol with substituted benzoic acids in the presence of polyphosphoric acid. The screening for antitumour activity was done as per the National Cancer Institute Drug Screening Strategy 1985. Three compounds were found to be significantly cytotoxic as compared to Cisplatin against the EAC induced mice.

M3 - Article

SN - 0971-1627

VL - 15

SP - 99

EP - 100

JO - Indian Journal of Heterocyclic Chemistry

JF - Indian Journal of Heterocyclic Chemistry

IS - 1

ER -

New benzoxazoles as potential antitumor agents

Abstract

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