Non-invasive drug delivery is an emerging way to target a wide range of therapeutics. One of them, i.e., the nasal drug delivery has shown promising results in delivering small and large molecules, genes, peptides, and proteins. This drug delivery system targets the drug to the brain by direct nose-to-brain and/or indirect nose-to-blood-to-brain routes. Nanocarriers play a vital role in the nasal delivery system due to their small size which provides ease in targeting. Numerous strategies have been explored by researchers for the transportation of drugs from nose to target and found excellent results in therapy. It was observed that polymeric and lipidic nanocarriers have numerous applications in targeted drug delivery, gene delivery, and vaccine delivery. Moreover, they are also used for diagnostics as well as theranostics purposes. This chapter briefly summarizes the different types of nanocarriers used for nasal delivery with their characterization techniques. Further, the biomedical applications of nan...

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Abstract

Non-invasive drug delivery is an emerging way to target a wide range of therapeutics. One of them, i.e., the nasal drug delivery has shown promising results in delivering small and large molecules, genes, peptides, and proteins. This drug delivery system targets the drug to the brain by direct nose-to-brain and/or indirect nose-to-blood-to-brain routes. Nanocarriers play a vital role in the nasal delivery system due to their small size which provides ease in targeting. Numerous strategies have been explored by researchers for the transportation of drugs from nose to target and found excellent results in therapy. It was observed that polymeric and lipidic nanocarriers have numerous applications in targeted drug delivery, gene delivery, and vaccine delivery. Moreover, they are also used for diagnostics as well as theranostics purposes. This chapter briefly summarizes the different types of nanocarriers used for nasal delivery with their characterization techniques. Further, the biomedical applications of nanocarriers via the nasal route are discussed in detail.

Original languageEnglish
Title of host publicationNasal Drug Delivery
Subtitle of host publicationFormulations, Developments, Challenges, and Solutions
PublisherSpringer International Publishing AG
Pages101-126
Number of pages26
ISBN (Electronic)9783031231124
ISBN (Print)9783031231117
DOIs
Publication statusPublished - 01-01-2023

All Science Journal Classification (ASJC) codes

  • General Biochemistry,Genetics and Molecular Biology
  • General Medicine
  • Pharmacology, Toxicology and Pharmaceutics(all)

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