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Norovirus Infection in Children with Acute Lymphoblastic Leukemia

Research output: Contribution to journalArticlepeer-review

Abstract

Norovirus infection in children on treatment for acute lymphoblastic leukemia can lead to severe morbidity due to chronic viral shedding, malabsorption, failure to thrive, and interruption of chemotherapy. We had four children with norovirus diarrhoea in eight years period in our pediatric oncology unit. Three children under two years of age had chronic noroviral shedding and persistent diarrhoea, probably due to poor adaptive immune responses. Two of those children didn’t respond to nitazoxanide and succumbed to the illness. The third patient who received nitazoxanide and favipiravir, is currently well on chemotherapy.

Original languageEnglish
Pages (from-to)403-407
Number of pages5
JournalInfection and Chemotherapy
Volume55
Issue number3
DOIs
Publication statusPublished - 09-2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Pharmacology (medical)

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