TY - JOUR
T1 - Norovirus Infection in Children with Acute Lymphoblastic Leukemia
AU - Reddy, Nalla Anuraag
AU - Raj, Keerthi
AU - Lashkari, Harsha Prasada
N1 - Publisher Copyright:
Copyright © 2023 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS.
PY - 2023/9
Y1 - 2023/9
N2 - Norovirus infection in children on treatment for acute lymphoblastic leukemia can lead to severe morbidity due to chronic viral shedding, malabsorption, failure to thrive, and interruption of chemotherapy. We had four children with norovirus diarrhoea in eight years period in our pediatric oncology unit. Three children under two years of age had chronic noroviral shedding and persistent diarrhoea, probably due to poor adaptive immune responses. Two of those children didn’t respond to nitazoxanide and succumbed to the illness. The third patient who received nitazoxanide and favipiravir, is currently well on chemotherapy.
AB - Norovirus infection in children on treatment for acute lymphoblastic leukemia can lead to severe morbidity due to chronic viral shedding, malabsorption, failure to thrive, and interruption of chemotherapy. We had four children with norovirus diarrhoea in eight years period in our pediatric oncology unit. Three children under two years of age had chronic noroviral shedding and persistent diarrhoea, probably due to poor adaptive immune responses. Two of those children didn’t respond to nitazoxanide and succumbed to the illness. The third patient who received nitazoxanide and favipiravir, is currently well on chemotherapy.
UR - https://www.scopus.com/pages/publications/85175056776
UR - https://www.scopus.com/pages/publications/85175056776#tab=citedBy
U2 - 10.3947/ic.2023.0058
DO - 10.3947/ic.2023.0058
M3 - Article
AN - SCOPUS:85175056776
SN - 2093-2340
VL - 55
SP - 403
EP - 407
JO - Infection and Chemotherapy
JF - Infection and Chemotherapy
IS - 3
ER -
