Abstract
Melphalan dimer is an impurity from the synthesis of Melphalan (M216900) which is an antineoplastic agent. In this article, a new route for the synthesis of Melphalan dimer impurity G has been discussed. The new research provides the first high-yield, high-purity synthesis of this impurity. The impurity has been confirmed for purity using HPLC, and its structure has been identified using MS, H and C NMR.
| Original language | English |
|---|---|
| Pages (from-to) | 313-317 |
| Number of pages | 5 |
| Journal | Indian Journal of Chemistry (IJC) |
| Volume | 62 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 04-2023 |
All Science Journal Classification (ASJC) codes
- General Pharmacology, Toxicology and Pharmaceutics
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry
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