Omega-3 fatty acids: A comprehensive review of their role in health and disease

B. M. Yashodhara, S. Umakanth, J. M. Pappachan, S. K. Bhat, R. Kamath, B. H. Choo

Research output: Contribution to journalReview articlepeer-review

247 Citations (Scopus)


Omega-3 fatty acids (ω-3 FAs) are essential fatty acids with diverse biological effects in human health and disease. Reduced cardiovascular morbidity and mortality is a well-established benefit of their intake. Dietary supplementation may also benefit patients with dys-lipidaemia, atherosclerosis, hypertension, diabetes mellitus, metabolic syndrome, obesity, inflammatory diseases, neurological/neuropsychiatric disorders and eye diseases. Consumption of co-3 FAs during pregnancy reduces the risk of premature birth and improves intellectual development of the fetus. Fish, fish oils and some vegetable oils are rich sources of ω-3 FAs. According to the UK Scientific Advisory Committee on Nutrition guidelines (2004), a healthy adult should consume a minimum of two portions of fish a week to obtain the health benefit. This review outlines the health implications, dietary sources, deficiency states and recommended allowances of c-3 FAs in relation to human nutrition.

Original languageEnglish
Pages (from-to)84-90
Number of pages7
JournalPostgraduate Medical Journal
Issue number1000
Publication statusPublished - 01-02-2009

All Science Journal Classification (ASJC) codes

  • General Medicine


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