Omics technologies in personalized combination therapy for cardiovascular diseases: Challenges and opportunities

Saradindu Banerjee; Navya Prabhu Basrur; Padmalatha S. Rai

doi:10.2217/pme-2021-0087

Omics technologies in personalized combination therapy for cardiovascular diseases: Challenges and opportunities

Saradindu Banerjee
, Navya Prabhu Basrur
, Padmalatha S. Rai^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

15 Citations (Scopus)

Abstract

The primary purpose of 'omics' technologies is to understand the intricacy of genomics, proteomics, metabolomics and other molecular mechanisms to reveal the complex traits of human diseases. The significant use of omics technologies and their applications in medicine gear up the study of the pathogenesis of several disorders. The detection of biomarkers in the early onset of diseases is challenging; still, omics can discover novel molecular mechanisms and biomarkers. In this review, the different types of omics and their technologies are explicated and aimed to provide their emerging applications in cardiovascular precision medicine. These technologies significantly impact optimizing medical treatment for individuals to reach a higher level in precision medicine.

Original language	English
Pages (from-to)	595-611
Number of pages	17
Journal	Personalized Medicine
Volume	18
Issue number	6
DOIs	https://doi.org/10.2217/pme-2021-0087
Publication status	Published - 11-2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Molecular Medicine
Pharmacology

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10.2217/pme-2021-0087

Cite this

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title = "Omics technologies in personalized combination therapy for cardiovascular diseases: Challenges and opportunities",

abstract = "The primary purpose of 'omics' technologies is to understand the intricacy of genomics, proteomics, metabolomics and other molecular mechanisms to reveal the complex traits of human diseases. The significant use of omics technologies and their applications in medicine gear up the study of the pathogenesis of several disorders. The detection of biomarkers in the early onset of diseases is challenging; still, omics can discover novel molecular mechanisms and biomarkers. In this review, the different types of omics and their technologies are explicated and aimed to provide their emerging applications in cardiovascular precision medicine. These technologies significantly impact optimizing medical treatment for individuals to reach a higher level in precision medicine. ",

author = "Saradindu Banerjee and \{Prabhu Basrur\}, Navya and Rai, \{Padmalatha S.\}",

note = "Funding Information: This study was supported by Indian Council of Medical Research (ICMR) (grant no. 2020-6122/CMB-BMS) and Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript. Publisher Copyright: {\textcopyright} 2021 Future Medicine Ltd.",

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AU - Prabhu Basrur, Navya

AU - Rai, Padmalatha S.

N1 - Funding Information: This study was supported by Indian Council of Medical Research (ICMR) (grant no. 2020-6122/CMB-BMS) and Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript. Publisher Copyright: © 2021 Future Medicine Ltd.

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N2 - The primary purpose of 'omics' technologies is to understand the intricacy of genomics, proteomics, metabolomics and other molecular mechanisms to reveal the complex traits of human diseases. The significant use of omics technologies and their applications in medicine gear up the study of the pathogenesis of several disorders. The detection of biomarkers in the early onset of diseases is challenging; still, omics can discover novel molecular mechanisms and biomarkers. In this review, the different types of omics and their technologies are explicated and aimed to provide their emerging applications in cardiovascular precision medicine. These technologies significantly impact optimizing medical treatment for individuals to reach a higher level in precision medicine.

AB - The primary purpose of 'omics' technologies is to understand the intricacy of genomics, proteomics, metabolomics and other molecular mechanisms to reveal the complex traits of human diseases. The significant use of omics technologies and their applications in medicine gear up the study of the pathogenesis of several disorders. The detection of biomarkers in the early onset of diseases is challenging; still, omics can discover novel molecular mechanisms and biomarkers. In this review, the different types of omics and their technologies are explicated and aimed to provide their emerging applications in cardiovascular precision medicine. These technologies significantly impact optimizing medical treatment for individuals to reach a higher level in precision medicine.

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DO - 10.2217/pme-2021-0087

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AN - SCOPUS:85120163820

SN - 1741-0541

VL - 18

SP - 595

EP - 611

JO - Personalized Medicine

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IS - 6

ER -

Omics technologies in personalized combination therapy for cardiovascular diseases: Challenges and opportunities

Abstract

UN SDGs

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