TY - JOUR
T1 - Optic neuropathy induced by low dose of ethambutol
T2 - A rare presentation
AU - Addoor, Krishna Rao
AU - Janardhana Raju, Vuppalapati Nishant
AU - Bhandary, Sulatha V.
AU - Menon, Sudha Girish
AU - Gupta, Aakanksha
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Ethambutol is a bacteriostatic antimicrobial agent used in the treatment of tuberculosis. Optic neuropathy is a potentially severe side effect of ethambutol, which is dose related. Ethambutol-induced optic neuropathy (EON) incidence is 15%, 5%, and 1% when taken at 50, 25, and 15 mg/kg/day, respectively, for 3 months. Hence, we report a case of bilateral EON in 20-year-old female after 1 month of exposure to 15 mg/kg/day of ethambutol for tubercular meningitis. Ophthalmologic examination revealed bilateral ill sustained pupillary reactions and optic disc pallor. Deranged color vision test and scotomas on Goldmann perimetry in both eyes, aided in diagnosis.
AB - Ethambutol is a bacteriostatic antimicrobial agent used in the treatment of tuberculosis. Optic neuropathy is a potentially severe side effect of ethambutol, which is dose related. Ethambutol-induced optic neuropathy (EON) incidence is 15%, 5%, and 1% when taken at 50, 25, and 15 mg/kg/day, respectively, for 3 months. Hence, we report a case of bilateral EON in 20-year-old female after 1 month of exposure to 15 mg/kg/day of ethambutol for tubercular meningitis. Ophthalmologic examination revealed bilateral ill sustained pupillary reactions and optic disc pallor. Deranged color vision test and scotomas on Goldmann perimetry in both eyes, aided in diagnosis.
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U2 - 10.22159/ajpcr.2017.v10i4.16983
DO - 10.22159/ajpcr.2017.v10i4.16983
M3 - Article
AN - SCOPUS:85017101852
SN - 0974-2441
VL - 10
SP - 12
EP - 13
JO - Asian Journal of Pharmaceutical and Clinical Research
JF - Asian Journal of Pharmaceutical and Clinical Research
IS - 4
ER -
