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Oxidant-antioxidant status in colorectal cancer patients - Before and after treatment

  • Sharmila Upadhya
  • , Subramanya Upadhya
  • , S. Krishna Mohan
  • , K. Vanajakshamma
  • , Mamatha Kunder
  • , Seema Mathias

Research output: Contribution to journalArticlepeer-review

Abstract

Erythrocyte antioxidant glutathione and malondialdehyde levels in erythrocytes and plasma glutathione S-transferase levels were estimated in patients with colorectal cancer and compared to controls. Further, the patients underwent four weeks of radiotherapy with adjuvant chemotherapy. The same parameters were estimated after four weeks of radiotherapy and compared with pretreatment levels. It was observed that there was a decrease in erythrocyte glutathione and malondialdehyde levels in patients with colorectal cancer compared to controls, but not in case of GST. However, after chemoradiotherapy, there were no statistically significant differences in all the parameters studied.

Original languageEnglish
Pages (from-to)80-83
Number of pages4
JournalIndian Journal of Clinical Biochemistry
Volume19
Issue number2
DOIs
Publication statusPublished - 01-01-2004
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

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