Benzyl and 1-phenylethyl bromides are oxidised to benzaldehyde and acetophenone respectively by DMSO in the presence of zinc salts with moderate to high yield. The corresponding alcohol and the thiomethyl ether derivative are formed as by-products. However, 2-phenylethyl bromide affords, under forcing conditions, the corresponding thiomethyl ether and alcohol as major products. This study, besides leading to a new variant of Kornblum oxidation, has given an insight into its mechanism.
|Number of pages
|Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry
|Published - 02-2004
All Science Journal Classification (ASJC) codes
- Pharmacology, Toxicology and Pharmaceutics(all)
- Organic Chemistry