Oxygen radiacl scavenging activity of phenylbutenones and their correlation with antiinflammatory activity

L.A. Saldanha; G. Elias; M.N.A. Rao

Oxygen radiacl scavenging activity of phenylbutenones and their correlation with antiinflammatory activity

L.A. Saldanha
, G. Elias
, M.N.A. Rao

Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

56 Citations (Scopus)

Abstract

A number of ring substituted (E-)-4-phenyl-3-buten-2-ones including dehydrozingerone were studied for their oxygen radical scavenging properties. They scavenged superoxide and hydroxyl radicals to an appreciable extent. Good correlation (r = 0.87) was obtained between superoxide scavenging and antiinflammatory activity. The correlation was not significant with the hydroxyl scavenging activity.

Original language	Undefined/Unknown
Pages (from-to)	89-91
Number of pages	3
Journal	Arzneimittel-Forschung/Drug Research
Volume	40
Issue number	1
Publication status	Published - 1990

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Cite this

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title = "Oxygen radiacl scavenging activity of phenylbutenones and their correlation with antiinflammatory activity",

abstract = "A number of ring substituted (E-)-4-phenyl-3-buten-2-ones including dehydrozingerone were studied for their oxygen radical scavenging properties. They scavenged superoxide and hydroxyl radicals to an appreciable extent. Good correlation (r = 0.87) was obtained between superoxide scavenging and antiinflammatory activity. The correlation was not significant with the hydroxyl scavenging activity.",

author = "L.A. Saldanha and G. Elias and M.N.A. Rao",

note = "cited By 47",

year = "1990",

language = "Undefined/Unknown",

volume = "40",

pages = "89--91",

journal = "Arzneimittel-Forschung/Drug Research",

issn = "2194-9379",

publisher = "Georg Thieme Verlag",

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T1 - Oxygen radiacl scavenging activity of phenylbutenones and their correlation with antiinflammatory activity

AU - Saldanha, L.A.

AU - Elias, G.

AU - Rao, M.N.A.

N1 - cited By 47

PY - 1990

Y1 - 1990

N2 - A number of ring substituted (E-)-4-phenyl-3-buten-2-ones including dehydrozingerone were studied for their oxygen radical scavenging properties. They scavenged superoxide and hydroxyl radicals to an appreciable extent. Good correlation (r = 0.87) was obtained between superoxide scavenging and antiinflammatory activity. The correlation was not significant with the hydroxyl scavenging activity.

AB - A number of ring substituted (E-)-4-phenyl-3-buten-2-ones including dehydrozingerone were studied for their oxygen radical scavenging properties. They scavenged superoxide and hydroxyl radicals to an appreciable extent. Good correlation (r = 0.87) was obtained between superoxide scavenging and antiinflammatory activity. The correlation was not significant with the hydroxyl scavenging activity.

M3 - Article

SN - 2194-9379

VL - 40

SP - 89

EP - 91

JO - Arzneimittel-Forschung/Drug Research

JF - Arzneimittel-Forschung/Drug Research

IS - 1

ER -