Paget's disease of bone: An entity still exists in India

Kripa Elizabeth Cherian, Nitin Kapoor, Sahana Shetty, Felix K. Jebasingh, Hesarghatta Shyamasunder Asha, Julie Hephzibah, Anne Jennifer Prabhu, Simon Rajaratnam, Nihal Thomas, Thomas Vizhalil Paul

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Background: Paget's disease of bone (PDB) is uncommonly reported from India. We attempted to study the clinical and imaging features and management of participants who presented with PDB. Materials and Methods: In this retrospective study, clinical and imaging profile, biochemistry, and treatment outcomes of participants with PDB (n = 48) were obtained. Results: The mean age was 60 ± 11.3 years and 35% were women. Twenty percent were asymptomatic. Many (87%) had polyostotic involvement. Sixty percent (n = 29) underwent treatment with zoledronic acid and rest with oral bisphosphonates, and all achieved remission. Conclusion: Most of the pagetic participants had polyostotic disease and one-fifth were asymptomatic. All participants had disease remission following treatment.

Original languageEnglish
Pages (from-to)368-372
Number of pages5
JournalIndian Journal of Endocrinology and Metabolism
Volume22
Issue number3
DOIs
Publication statusPublished - 01-05-2018

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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