TY - JOUR
T1 - Paget's disease of bone
T2 - An entity still exists in India
AU - Cherian, Kripa Elizabeth
AU - Kapoor, Nitin
AU - Shetty, Sahana
AU - Jebasingh, Felix K.
AU - Asha, Hesarghatta Shyamasunder
AU - Hephzibah, Julie
AU - Prabhu, Anne Jennifer
AU - Rajaratnam, Simon
AU - Thomas, Nihal
AU - Paul, Thomas Vizhalil
N1 - Publisher Copyright:
© 2018 Indian Journal of Endocrinology and Metabolism | Published by Wolters Kluwer - Medknow.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Background: Paget's disease of bone (PDB) is uncommonly reported from India. We attempted to study the clinical and imaging features and management of participants who presented with PDB. Materials and Methods: In this retrospective study, clinical and imaging profile, biochemistry, and treatment outcomes of participants with PDB (n = 48) were obtained. Results: The mean age was 60 ± 11.3 years and 35% were women. Twenty percent were asymptomatic. Many (87%) had polyostotic involvement. Sixty percent (n = 29) underwent treatment with zoledronic acid and rest with oral bisphosphonates, and all achieved remission. Conclusion: Most of the pagetic participants had polyostotic disease and one-fifth were asymptomatic. All participants had disease remission following treatment.
AB - Background: Paget's disease of bone (PDB) is uncommonly reported from India. We attempted to study the clinical and imaging features and management of participants who presented with PDB. Materials and Methods: In this retrospective study, clinical and imaging profile, biochemistry, and treatment outcomes of participants with PDB (n = 48) were obtained. Results: The mean age was 60 ± 11.3 years and 35% were women. Twenty percent were asymptomatic. Many (87%) had polyostotic involvement. Sixty percent (n = 29) underwent treatment with zoledronic acid and rest with oral bisphosphonates, and all achieved remission. Conclusion: Most of the pagetic participants had polyostotic disease and one-fifth were asymptomatic. All participants had disease remission following treatment.
UR - https://www.scopus.com/pages/publications/85050375051
UR - https://www.scopus.com/pages/publications/85050375051#tab=citedBy
U2 - 10.4103/ijem.IJEM-19-18
DO - 10.4103/ijem.IJEM-19-18
M3 - Article
AN - SCOPUS:85050375051
SN - 2230-8210
VL - 22
SP - 368
EP - 372
JO - Indian Journal of Endocrinology and Metabolism
JF - Indian Journal of Endocrinology and Metabolism
IS - 3
ER -
