Papillary glioneuronal tumor - Evidence of stem cell origin with biphenotypic differentiation

Aparna Govindan; Anita Mahadevan; D. I. Bhat; A. Arivazhagan; Shrijeet Chakraborti; M. S. Suja; A. A. Phalguni; S. Sampath; B. A. Chandramouli; S. K. Shankar

doi:10.1007/s11060-009-9893-5

Papillary glioneuronal tumor - Evidence of stem cell origin with biphenotypic differentiation

Aparna Govindan, Anita Mahadevan, D. I. Bhat, A. Arivazhagan, Shrijeet Chakraborti, M. S. Suja, A. A. Phalguni, S. Sampath, B. A. Chandramouli, S. K. Shankar

Department of Pathology, Kasturba Medical College, Mangalore

Research output: Contribution to journal › Article › peer-review

23 Citations (SciVal)

Abstract

Papillary glioneuronal tumors are newly recognized seizure producing tumors. We report two such cases with immunohistochemical characterization of glial and neuronal components and briefly review literature. Co-localization of glial and neuronal markers was demonstrable on confocal microscopy with expression of stem cell markers (Nestin and CD133) suggesting possible origin from neuroepithelial stem cell with biphenotypic differentiation.

Original language	English
Pages (from-to)	71-80
Number of pages	10
Journal	Journal of Neuro-Oncology
Volume	95
Issue number	1
DOIs	https://doi.org/10.1007/s11060-009-9893-5
Publication status	Published - 30-04-2009

All Science Journal Classification (ASJC) codes

Clinical Neurology
Cancer Research
Oncology
Neurology

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10.1007/s11060-009-9893-5

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abstract = "Papillary glioneuronal tumors are newly recognized seizure producing tumors. We report two such cases with immunohistochemical characterization of glial and neuronal components and briefly review literature. Co-localization of glial and neuronal markers was demonstrable on confocal microscopy with expression of stem cell markers (Nestin and CD133) suggesting possible origin from neuroepithelial stem cell with biphenotypic differentiation.",

author = "Aparna Govindan and Anita Mahadevan and Bhat, {D. I.} and A. Arivazhagan and Shrijeet Chakraborti and Suja, {M. S.} and Phalguni, {A. A.} and S. Sampath and Chandramouli, {B. A.} and Shankar, {S. K.}",

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doi = "10.1007/s11060-009-9893-5",

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T1 - Papillary glioneuronal tumor - Evidence of stem cell origin with biphenotypic differentiation

AU - Govindan, Aparna

AU - Mahadevan, Anita

AU - Bhat, D. I.

AU - Arivazhagan, A.

AU - Chakraborti, Shrijeet

AU - Suja, M. S.

AU - Phalguni, A. A.

AU - Sampath, S.

AU - Chandramouli, B. A.

AU - Shankar, S. K.

PY - 2009/4/30

Y1 - 2009/4/30

N2 - Papillary glioneuronal tumors are newly recognized seizure producing tumors. We report two such cases with immunohistochemical characterization of glial and neuronal components and briefly review literature. Co-localization of glial and neuronal markers was demonstrable on confocal microscopy with expression of stem cell markers (Nestin and CD133) suggesting possible origin from neuroepithelial stem cell with biphenotypic differentiation.

AB - Papillary glioneuronal tumors are newly recognized seizure producing tumors. We report two such cases with immunohistochemical characterization of glial and neuronal components and briefly review literature. Co-localization of glial and neuronal markers was demonstrable on confocal microscopy with expression of stem cell markers (Nestin and CD133) suggesting possible origin from neuroepithelial stem cell with biphenotypic differentiation.

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Papillary glioneuronal tumor - Evidence of stem cell origin with biphenotypic differentiation

Abstract

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