Phenytoin-induced acute generalized exanthematous pustulosis

Navin Patil; Sushil Kiran Kunder; A. Avinash; Anurag Pathak; Sharath Madhyastha; N. Karthik Rao; Raghavendra Rao

Phenytoin-induced acute generalized exanthematous pustulosis

Navin Patil, Sushil Kiran Kunder, A. Avinash, Anurag Pathak, Sharath Madhyastha, N. Karthik Rao, Raghavendra Rao

Research output: Contribution to journal › Article › peer-review

Abstract

Phenytoin is the first line antiepileptic for generalized tonic-clonic seizures. It is still the “go to” drug despite the availability of newer anti-epileptics, chiefly because of its low cost and high efficacy. Phenytoin is associated with toxicities involving multiple organ systems such as brain, blood, and skin. One of the most common adverse effects is the development of skin rashes. It can range from mild to life-threatening skin eruptions. This is a case report of a young girl who developed acute generalized exanthematous pustulosis following phenytoin therapy for post-traumatic seizures.

Original language	English
Pages (from-to)	10-11
Number of pages	2
Journal	Asian Journal of Pharmaceutical and Clinical Research
Volume	9
Issue number	2
Publication status	Published - 01-03-2016

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmaceutical Science
Pharmacology (medical)

Cite this

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title = "Phenytoin-induced acute generalized exanthematous pustulosis",

abstract = "Phenytoin is the first line antiepileptic for generalized tonic-clonic seizures. It is still the “go to” drug despite the availability of newer anti-epileptics, chiefly because of its low cost and high efficacy. Phenytoin is associated with toxicities involving multiple organ systems such as brain, blood, and skin. One of the most common adverse effects is the development of skin rashes. It can range from mild to life-threatening skin eruptions. This is a case report of a young girl who developed acute generalized exanthematous pustulosis following phenytoin therapy for post-traumatic seizures.",

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AU - Kunder, Sushil Kiran

AU - Avinash, A.

AU - Pathak, Anurag

AU - Madhyastha, Sharath

AU - Karthik Rao, N.

AU - Rao, Raghavendra

PY - 2016/3/1

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N2 - Phenytoin is the first line antiepileptic for generalized tonic-clonic seizures. It is still the “go to” drug despite the availability of newer anti-epileptics, chiefly because of its low cost and high efficacy. Phenytoin is associated with toxicities involving multiple organ systems such as brain, blood, and skin. One of the most common adverse effects is the development of skin rashes. It can range from mild to life-threatening skin eruptions. This is a case report of a young girl who developed acute generalized exanthematous pustulosis following phenytoin therapy for post-traumatic seizures.

AB - Phenytoin is the first line antiepileptic for generalized tonic-clonic seizures. It is still the “go to” drug despite the availability of newer anti-epileptics, chiefly because of its low cost and high efficacy. Phenytoin is associated with toxicities involving multiple organ systems such as brain, blood, and skin. One of the most common adverse effects is the development of skin rashes. It can range from mild to life-threatening skin eruptions. This is a case report of a young girl who developed acute generalized exanthematous pustulosis following phenytoin therapy for post-traumatic seizures.

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Phenytoin-induced acute generalized exanthematous pustulosis

Abstract

All Science Journal Classification (ASJC) codes

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