TY - JOUR
T1 - Photonics of human saliva
T2 - potential optical methods for the screening of abnormal health conditions and infections
AU - Lukose, Jijo
AU - Sanoop Pavithran, M.
AU - Mithun, N.
AU - Barik, Ajaya Kumar
AU - Pai, Keerthilatha M.
AU - Unnikrishnan, V. K.
AU - George, Sajan D.
AU - Kartha, V. B.
AU - Chidangil, Santhosh
N1 - Publisher Copyright:
© 2021, The Author(s).
PY - 2021
Y1 - 2021
N2 - Human saliva can be treated as a pool of biological markers able to reflect on the state of personal health. Recent years have witnessed an increase in the use of optical devices for the analysis of body fluids. Several groups have carried out studies investigating the potential of saliva as a non-invasive and reliable clinical specimen for use in medical diagnostics. This brief review aims to highlight the optical technologies, mainly surface plasmon resonance (SPR), Raman, and Fourier transform infrared (FTIR) spectroscopy, which are being used for the probing of saliva for diverse biomedical applications. Advances in bio photonics offer the promise of unambiguous, objective and fast detection of abnormal health conditions and viral infections (such as COVID-19) from the analysis of saliva.
AB - Human saliva can be treated as a pool of biological markers able to reflect on the state of personal health. Recent years have witnessed an increase in the use of optical devices for the analysis of body fluids. Several groups have carried out studies investigating the potential of saliva as a non-invasive and reliable clinical specimen for use in medical diagnostics. This brief review aims to highlight the optical technologies, mainly surface plasmon resonance (SPR), Raman, and Fourier transform infrared (FTIR) spectroscopy, which are being used for the probing of saliva for diverse biomedical applications. Advances in bio photonics offer the promise of unambiguous, objective and fast detection of abnormal health conditions and viral infections (such as COVID-19) from the analysis of saliva.
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U2 - 10.1007/s12551-021-00807-8
DO - 10.1007/s12551-021-00807-8
M3 - Review article
AN - SCOPUS:85106669316
SN - 1867-2450
VL - 13
SP - 359
EP - 385
JO - Biophysical Reviews
JF - Biophysical Reviews
IS - 3
ER -
