TY - JOUR
T1 - Pilot study of salivary butyrylcholinesterase, phosphodiesterase, thiols and cerulopalsmin in auditory neuropathy
AU - Hari Prakash, Prakash
AU - Prabhu, Krishnananda
AU - Poojari, Kailesh
AU - Prabhu, Bhavya
AU - Malik, Rimshida
AU - Rao, Anjali
PY - 2012/11/20
Y1 - 2012/11/20
N2 - Objective: To estimate butyrylcholinesterase (BChE), phosphodiesterase (PDE), thiols and cerulopalsmin by non - invasive means in saliva a of subjects (both cases and controls) and correlated to their hearing sensitivity. Methods: Total of 13 subjects participated in this study. Among them 7 were having auditory neuropathy and 6 were healthy controls. Unstimulated saliva (10 ml) was collected from each participant. Ceruloplasmin, thiols, phosphodiesterase and pseudocholinesterase were estimated by colorimetric method in the salivary samples. Results: Salivary BChE and PDE levels were marginally elevated and protein thiols were marginally decreased in cases as compared to that of controls. Salivary ceruloplasmin was significantly decreased (p = 0.022) in cases as compared to that of controls. Conclusions: Saliva can be used as a potential noninvasive tool for evaluation of disorders.
AB - Objective: To estimate butyrylcholinesterase (BChE), phosphodiesterase (PDE), thiols and cerulopalsmin by non - invasive means in saliva a of subjects (both cases and controls) and correlated to their hearing sensitivity. Methods: Total of 13 subjects participated in this study. Among them 7 were having auditory neuropathy and 6 were healthy controls. Unstimulated saliva (10 ml) was collected from each participant. Ceruloplasmin, thiols, phosphodiesterase and pseudocholinesterase were estimated by colorimetric method in the salivary samples. Results: Salivary BChE and PDE levels were marginally elevated and protein thiols were marginally decreased in cases as compared to that of controls. Salivary ceruloplasmin was significantly decreased (p = 0.022) in cases as compared to that of controls. Conclusions: Saliva can be used as a potential noninvasive tool for evaluation of disorders.
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U2 - 10.1016/S2222-1808(12)60205-9
DO - 10.1016/S2222-1808(12)60205-9
M3 - Article
AN - SCOPUS:84869124887
SN - 2222-1808
VL - 2
JO - Asian Pacific Journal of Tropical Disease
JF - Asian Pacific Journal of Tropical Disease
IS - SUPPL.1
ER -
