Poorly differentiated carcinoma of the anterior mediastinum in a young male - A diagnostic dilemma

Radha R. Pai; Prabha Adhikari; Ashok B. Shetty; C. V. Raghuveer

doi:10.1016/j.rmedc.2008.07.013

Poorly differentiated carcinoma of the anterior mediastinum in a young male - A diagnostic dilemma

Radha R. Pai, Prabha Adhikari, Ashok B. Shetty, C. V. Raghuveer

Department of Surgery, Kasturba Medical College, Mangalore

Research output: Contribution to journal › Article › peer-review

Abstract

A 22-year-old male with anterior mediastinal tumour had extensive local and metastatic disease at initial presentation. The diagnosis was based on tru-cut biopsy of the primary lesion and fine needle aspiration cytology of the metastatic deposit along with serum tumour marker studies. The biopsy as well as the cytology smears showed features of a poorly differentiated carcinoma, and both serum alpha-foeto-protein and hCG levels were elevated. A diagnosis of malignant mixed germ cell tumour was suggested. The patient achieved complete remission following cis-platin based chemotherapy and is disease free for the last 12 years.

Original language	English
Pages (from-to)	225-227
Number of pages	3
Journal	Respiratory Medicine CME
Volume	1
Issue number	3
DOIs	https://doi.org/10.1016/j.rmedc.2008.07.013
Publication status	Published - 25-09-2008

All Science Journal Classification (ASJC) codes

Pulmonary and Respiratory Medicine

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10.1016/j.rmedc.2008.07.013

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abstract = "A 22-year-old male with anterior mediastinal tumour had extensive local and metastatic disease at initial presentation. The diagnosis was based on tru-cut biopsy of the primary lesion and fine needle aspiration cytology of the metastatic deposit along with serum tumour marker studies. The biopsy as well as the cytology smears showed features of a poorly differentiated carcinoma, and both serum alpha-foeto-protein and hCG levels were elevated. A diagnosis of malignant mixed germ cell tumour was suggested. The patient achieved complete remission following cis-platin based chemotherapy and is disease free for the last 12 years.",

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N2 - A 22-year-old male with anterior mediastinal tumour had extensive local and metastatic disease at initial presentation. The diagnosis was based on tru-cut biopsy of the primary lesion and fine needle aspiration cytology of the metastatic deposit along with serum tumour marker studies. The biopsy as well as the cytology smears showed features of a poorly differentiated carcinoma, and both serum alpha-foeto-protein and hCG levels were elevated. A diagnosis of malignant mixed germ cell tumour was suggested. The patient achieved complete remission following cis-platin based chemotherapy and is disease free for the last 12 years.

AB - A 22-year-old male with anterior mediastinal tumour had extensive local and metastatic disease at initial presentation. The diagnosis was based on tru-cut biopsy of the primary lesion and fine needle aspiration cytology of the metastatic deposit along with serum tumour marker studies. The biopsy as well as the cytology smears showed features of a poorly differentiated carcinoma, and both serum alpha-foeto-protein and hCG levels were elevated. A diagnosis of malignant mixed germ cell tumour was suggested. The patient achieved complete remission following cis-platin based chemotherapy and is disease free for the last 12 years.

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Poorly differentiated carcinoma of the anterior mediastinum in a young male - A diagnostic dilemma

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