Prescribing patterns in Dengue fever in paediatric patients in a tertiary care hospital: A retrospective cross sectional study

  • U. Usha Rani*
  • , Sangita G. Kamath
  • , H. V. Varun
  • , Sathisha Aithal
  • , Umakant N. Patil
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Dengue fever (DF) is the most common arboviral infection of mankind gaining global attention. Prescribing patterns in DF helps to evaluate the present trends of drug usage, drug expenditures, appropriateness of prescriptions and adherence to evidence-based recommendations. To study the prescribing patterns, approval status, inclusion in World Health Organization essential medicines list (WHO-EML) and National List of Essential Medicines (NLEM), cost of drugs prescribed in the treatment of paediatric DF. Data was collected from medical records of DF paediatric in-patients of SSIMS & RC Hospital, Davangere. The prescribing patterns, approval of drugs by Drug Controller General of India (DCGI) and United States Food and Drug Administration (USFDA), cost of drugs and listing in WHO-EML and NLEM were analysed. The drugs were classified into different groups based on WHO-ATC (Anatomical Taxonomical Chemical) classification. Descriptive statistics was applied using MS Excel 2010. The commonly used treatment modalities in 136 DF cases were antipyretics (100%), intravenous fluids (IVFs) (97.1%), antiulcer agents (94.1%) and anti-emetics (79.4%). Of 512 drug prescriptions majority (93.6%) were single drug formulations. 99.2% of drug prescriptions were approved by DCGI and 97.3% by FDA. >87% of drugs were enlisted in NLEM and WHO-EML. Only 6.3% drugs were prescribed by generic names. The most commonly prescribed ATC class of drugs belonged to A02B, N02B and A04A. The costliest drug prescribed was Inj. Piperacillin+Tazobactam. The results showed that utmost priority was given to symptomatic management of dengue fever with antipyretics, intravenous fluids, antiulcer agents and anti-emetics.

Original languageEnglish
Pages (from-to)112-118
Number of pages7
JournalInternational Journal of Pharmaceutical Sciences Review and Research
Volume24
Issue number2
Publication statusPublished - 01-2014

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

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