Abstract
Vitamin D deficiency has been implicated in various diseases including cancer and auto immune diseases. The present study attempts to establish a relation between vitamin D deficiency, thyroid hormones and TSH in subclinical hypothyroidism.100 newly diagnosed patients with subclinical hypothyroidism were divided into three groups according to vitamin D levels. Mean plasma TSH and T3 values decreased with increasing vitamin D values and T4 increased with increasing vitamin D tertiles. However, intergroup comparison showed no statistically significant changes. In females, negative correlation between vitamin D and TSH was statistically significant (p=0.014).The prevalence of vitamin D deficiency, insufficiency and sufficiency in 100 patients was found to be 38%, 38% and 24%. The study indicates the prevalence of vitamin D deficiency in subclinical hypothyroidism, but further studies are needed to determine whether it is a causative factor in the pathogenesis of the disease or a consequence.
Original language | English |
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Pages (from-to) | B1380-B1384 |
Journal | International Journal of Pharma and Bio Sciences |
Volume | 4 |
Issue number | 4 |
Publication status | Published - 01-10-2013 |
All Science Journal Classification (ASJC) codes
- Biotechnology
- Biochemistry
- Molecular Biology
- Cell Biology