Pro-healing effect of betel nut and its polyphenols

P. N. Padmaja, K. L. Bairy, D. R. Kulkarni

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


The effects of betel nut (Areca catechu) extract and its two constituents, namely arecholine and polyphenols, were studied in male Wistar rats on three wound models viz. excision, incision and dead space wounds. The three drugs were given either topically or orally for incision and excision wounds whereas only orally for dead space wounds. Rate of wound contraction, period of epithelisation, wound breaking strength, granulation tissue weight and hydroxyproline content of granulation tissue were determined. The crude betel nut extract as well as polyphenols promoted wound healing, but arecholine did not influence it.

Original languageEnglish
Pages (from-to)298-300
Number of pages3
Issue number4
Publication statusPublished - 01-01-1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology


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