Probing the Influence of Heavy Metals on Protein Topology by Autofluorescence Spectroscopy

Thoshna; Shaik Basha; Anjana Pithakumar; Shanmukha Sreeya Devarakonda; Darshan Chikkanayakanahalli Mukunda; Jackson Rodrigues; Subhash Chandra; K. Ameera; Shimul Biswas; Krishna Kishore Mahato

Probing the Influence of Heavy Metals on Protein Topology by Autofluorescence Spectroscopy

Thoshna
, Shaik Basha
, Anjana Pithakumar
, Shanmukha Sreeya Devarakonda
, Darshan Chikkanayakanahalli Mukunda
, Jackson Rodrigues
, Subhash Chandra
, K. Ameera
, Shimul Biswas
, Krishna Kishore Mahato^*

^*Corresponding author for this work

Department of Biophysics, Manipal School of Life Sciences, Manipal

Research output: Contribution to conference › Paper › peer-review

1 Citation (Scopus)

Abstract

Heavy metals significantly impact the homeostasis of proteins. The current study investigates the influence of Zinc and Copper on protein structure alterations using autofluorescence spectroscopy. Further, modifications of proteins are validated by Thioflavin T assay.

Original language	English
Publication status	Published - 2024
Event	2024 Frontiers in Optics, FiO 2024 - Denver, United States Duration: 23-09-2024 → 26-09-2024

Conference

Conference	2024 Frontiers in Optics, FiO 2024
Country/Territory	United States
City	Denver
Period	23-09-24 → 26-09-24

All Science Journal Classification (ASJC) codes

Control and Systems Engineering
Electronic, Optical and Magnetic Materials
Instrumentation
General Computer Science
Space and Planetary Science
Electrical and Electronic Engineering
Atomic and Molecular Physics, and Optics

Cite this

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title = "Probing the Influence of Heavy Metals on Protein Topology by Autofluorescence Spectroscopy",

abstract = "Heavy metals significantly impact the homeostasis of proteins. The current study investigates the influence of Zinc and Copper on protein structure alterations using autofluorescence spectroscopy. Further, modifications of proteins are validated by Thioflavin T assay.",

author = "Thoshna and Shaik Basha and Anjana Pithakumar and Devarakonda, \{Shanmukha Sreeya\} and Mukunda, \{Darshan Chikkanayakanahalli\} and Jackson Rodrigues and Subhash Chandra and K. Ameera and Shimul Biswas and Mahato, \{Krishna Kishore\}",

note = "Publisher Copyright: {\textcopyright} Optica Publishing Group 2024, {\textcopyright} 2024 The Author(s); 2024 Frontiers in Optics, FiO 2024 ; Conference date: 23-09-2024 Through 26-09-2024",

year = "2024",

language = "English",

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TY - CONF

T1 - Probing the Influence of Heavy Metals on Protein Topology by Autofluorescence Spectroscopy

AU - Thoshna,

AU - Basha, Shaik

AU - Pithakumar, Anjana

AU - Devarakonda, Shanmukha Sreeya

AU - Mukunda, Darshan Chikkanayakanahalli

AU - Rodrigues, Jackson

AU - Chandra, Subhash

AU - Ameera, K.

AU - Biswas, Shimul

AU - Mahato, Krishna Kishore

PY - 2024

Y1 - 2024

N2 - Heavy metals significantly impact the homeostasis of proteins. The current study investigates the influence of Zinc and Copper on protein structure alterations using autofluorescence spectroscopy. Further, modifications of proteins are validated by Thioflavin T assay.

AB - Heavy metals significantly impact the homeostasis of proteins. The current study investigates the influence of Zinc and Copper on protein structure alterations using autofluorescence spectroscopy. Further, modifications of proteins are validated by Thioflavin T assay.

UR - https://www.scopus.com/pages/publications/85216009090

UR - https://www.scopus.com/pages/publications/85216009090#tab=citedBy

M3 - Paper

AN - SCOPUS:85216009090

T2 - 2024 Frontiers in Optics, FiO 2024

Y2 - 23 September 2024 through 26 September 2024

ER -

Probing the Influence of Heavy Metals on Protein Topology by Autofluorescence Spectroscopy

Abstract

Conference

All Science Journal Classification (ASJC) codes

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