Abstract
Proteomics based techniques are rapidly emerging as alternative techniques to conventional histo-pathological methods for detection and diagnosis of cancers. Tumor markers are of considerable importance in the study of various cancers. A study of various changes in the protein profile associated with breast cancer will facilitate a better understanding of the various dynamic changes associated with the disease. In our study we have used High Performance Liquid Chromatography coupled with highly sensitive Laser Induced Fluorescence for recording the protein profiles of breast tissue homogenates. The protein profiles were recorded from pathologically certified normal as well as malignant breast tissue samples. The recorded protein profiles were studied by using Principal Component Analysis. Good discrimination of normal, benign and malignant samples was achieved in this pilot study.
Original language | English |
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Title of host publication | Advanced Biomedical and Clinical Diagnostic Systems V |
Volume | 6430 |
DOIs | |
Publication status | Published - 2007 |
Event | Advanced Biomedical and Clinical Diagnostic Systems V - San Jose, CA, United States Duration: 21-01-2007 → 27-01-2007 |
Conference
Conference | Advanced Biomedical and Clinical Diagnostic Systems V |
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Country/Territory | United States |
City | San Jose, CA |
Period | 21-01-07 → 27-01-07 |
All Science Journal Classification (ASJC) codes
- Engineering(all)